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Author Topic: Understanding Type 2 Diabetes Mellitus  (Read 4222 times)
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« on: March 30, 2007, 02:29:37 am »

Type 2 Diabetes

 Type 2 diabetes, often called non-insulin dependant diabetes, is the most common form of diabetes, affecting 90% - 95% of the 18.2 million people with diabetes.

Unlike people with type 1 diabetes, people with type 2 diabetes produce insulin; however, the insulin their pancreas secretes is either not enough or the body is unable to recognize the insulin and use it properly. This is called insulin-resistance. When there isn't enough insulin or the insulin is not used as it should be, glucose (sugar) can't get into the body's cells. When glucose builds up in the blood instead of going into cells, the body's cells are not able to function properly. Other problems associated with the build up of glucose in the blood include:

    * Dehydration. The build up of sugar in the blood can cause an increase in urination (to try to clear the sugar from the body). When the kidneys lose the glucose through the urine, a large amount of water is also lost, causing dehydration.
    * Hyperosmolar nonketotic diabetic coma. When a person with type 2 diabetes becomes severely dehydrated and is not able to drink enough fluids to make up for the fluid losses, they may develop this life-threatening complication.
    * Damage to the body. Over time, the high glucose levels in the blood may damage the nerves and small blood vessels of the eyes, kidneys, and heart and predispose a person to atherosclerosis (hardening) of the large arteries that can cause heart attack and stroke.

Who gets type 2 diabetes?

Anyone can get type 2 diabetes. However, those at highest risk for the disease are those who are obese or overweight, women who have had gestational diabetes, people with family members who have type 2 diabetes and people who have metabolic syndrome (a cluster of problems that include high cholesterol, high triglycerides, low good 'HDL' cholesterol and a high bad 'LDL' cholesterol and high blood pressure). In addition, older people are more susceptible to developing the disease since aging makes the body less tolerant of sugars.

What causes type 2 diabetes?

Although it is more common than type 1 diabetes, type 2 diabetes is less well understood. It is likely caused by multiple factors and not a single problem. Type 2 diabetes can run in families, but the exact nature of how it's inherited or the identity of a single genetic factor is not known.

What are the symptoms?

The symptoms of type 2 diabetes vary from person to person but may include:

    * Increased thirst.
    * Increased hunger (especially after eating).
    * Dry mouth.
    * Nausea and occasionally vomiting.
    * Frequent urination.
    * Fatigue (weak, tired feeling).
    * Blurred vision.
    * Numbness or tingling of the hands or feet.
    * Frequent infections of the skin, urinary tract or vagina.

Rarely a person may be diagnosed with type 2 diabetes after presenting to the hospital in a diabetic coma.

How is it diagnosed?

If your health care provider suspects type 2 diabetes, he will first check for abnormalities in your blood (high blood glucose level). In addition, he may look for glucose or ketone bodies in your urine. Tests used to diagnose type 2 diabetes include a fasting plasma glucose test or a casual plasma glucose test. You will also need to check your blood sugar levels regularly.

Complications associated with type 2 diabetes

 If your diabetes isn't well controlled, there are a number of serious or life-threatening problems you may experience, including:

    * Retinopathy. People with type 2 diabetes may already have abnormalities in the eyes related to the development of diabetes. Over time more and more people who initially do not have eye problems related to the disease will develop some form of eye problem. It is important to control not only sugars but blood pressure and cholesterol to prevent progression of eye disease. Fortunately, the vision loss isn't significant in most.
    * Kidney damage. The risk for kidney disease increases over time, meaning the longer you have diabetes the greater your risk. This complication carries significant risk of serious illness -- such as kidney failure and heart disease.
    * Poor blood circulation and nerve damage. Damage to nerves and hardening of the arteries leads to decreased sensation and poor blood circulation in the feet. This can lead to increased infections and an increased risk of ulcers which heal poorly and can in turn significantly raises the risk of amputation. Damage to nerves may also lead to digestive problems, such as nausea, vomiting and diarrhea.

Source: http://www.medscape.com/viewarticle/464903
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peganjr
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« Reply #1 on: November 17, 2007, 04:35:05 pm »

http://www.diabetesmellitus.ws/ - Excellent site offering hundreds of articles about Type 1 & Type 2 Diabetes Mellitus.
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Peter Egan Jr

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« Reply #2 on: December 28, 2007, 04:24:39 am »

Hi,
this is a site that I found, check it out, you can find lots of medicine for diabetes and other halth information
http://www.trustedprescriptionsonline.com/diamicronmr
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« Reply #3 on: September 15, 2008, 08:12:28 pm »

Diabetes is one of what we call as "Modern Days Disease"
or "Rich People Disease". There are 6 causes of this
disease:

1. Air Polution
2. Water Polution
3. Stress
4. Lack of exercise
5. Lack of rest (Busy lifestyle)
6. Unbalance Diet

All these 6 factors were the outcome from the
modern world we live today. Is this the price we
need to pay for the advance technology?

Medical Technologies are become more advance
and yet people's health condition become worst.
Why is this happening?

During the days of our grandfathers, they don't
even have to know about Diabetes because it is
a rare disease to them. But today, it is a
"wait and get" disease to majority of the people.

So what can we do is to bring back our body's
ability to heal itself.
"Body = Best Doctor"

Try to avoid drugs medicine as it is just for
controling. There's a lot more I want to share
but let it stop here for now. Smiley

I am spreading about health concept right now
but this is just the tiny piece of it.


Regards,

Tim
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amanda
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« Reply #4 on: August 19, 2009, 11:56:02 pm »

when you have type 2 diabetes, high levels of sugar build up in your blood. and it will lead you into serious health complications. that's why upon controlling your blood sugar is a key to managing diabetes. keeping your blood sugar under control and lowers your risk for complications later. high blood sugar can harm your organs and it will raise the risk of heart disease. hope that my small info helps.
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mischelstraus
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« Reply #5 on: February 05, 2010, 01:21:54 pm »

First, very well researched article, thank you!
I always love to learn more about natural treatment for medical conditions.

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dB
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« Reply #6 on: May 18, 2010, 12:39:38 am »

hello all.! I am interested to know if anyone knows of any complementary treatment methods, or came across articles/journals using traditional chinese medicine and western medication to treat diabetes type 1 & 2? Thank you very much.!
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« Reply #7 on: August 19, 2010, 01:16:58 am »

A well written post, but I would like to elaborate on the complications of diabetes.


If a diabetic patient does not take care in controlling this disease, he is definitely asking for trouble—big trouble. Several complications arise which are   crippling. To understand the “how and why” of the   complications, it is recommended that you also read our “Diabetes and cholesterol”

Let us see what these complications are :

1)  Diabetes and Heart:
                                       A diabetic runs double the risk of contracting a heart disease or stroke. Chances are that a diabetic, who has had a heart attack once, has a greater risk of getting another one.

                                  Higher sugar or higher glucose levels in the blood cause fats to be deposited on the inner walls of the blood vessels, which causes the walls of the blood vessels to thicken and harden. This results in clogging of the arteries and reduced blood supply to the heart causing a heart attack. 

2) Diabetic retinopathy:
                                        In a patient of long standing diabetes, the retina starts getting damaged gradually. Diabetes is associated with high blood pressure and the combination of these two causes damage to the smaller blood vessels of the eye. These blood vessels get clogged, brittle   and weakened causing them to rupture.

                          Blood gets released into the vitreous fluid,   which fills the eye ball. This fluid loses its transparency and the light  rays   which   enter the eye do not reach the retina, resulting in impairment of vision. There may be double vision, or blurring of vision, or flashing lights or dark spots in front of the eyes. The patient also experiences pain in both the eyes and peripheral vision is lost.

                        It is imperative therefore, that a diabetic patient should get his eyes checked regularly.


3) Diabetic neuropathy:  As this topic requires a more detailed write up, I have written a separate post on it, titled “ Diabetic neuropathy – a serious complication of diabetes”.   A brief mention here is made though:

 More than 70% of the patients, with a long history of diabetes,  have this complication of neuropathy. As explained earlier, in diabetes, the blood vessels get damaged.

              As a result of this damage to the small blood vessels supplying the nerves, the nerves do not get sufficient blood supply and thus complications of neuropathy occur. Any nerve or its segment in the body could get affected.

             The symptoms of diabetic neuropathy thus depend on the nerve that is affected. The symptoms could therefore be peripheral or autonomous.

Peripheral nerve damage symptoms could thus be those relating to the hands and feet like tingling  and numbness, loss of sensation, non healing ulcer on the foot,  among other things.

Autonomous nerve damage  symptoms could be those relating to heart or the digestive tract or the kidneys and urinary bladder. Explained in detail in
“ Diabetic neuropathy — a serious problem”

5) Erectile  dysfunction:  As explained earlier, diabetes causes clogging of the arteries and damage to the nerves. Since penile erection depends on a sequence of events in which blood vessels and the nerves play an important role, erection can be hampered. Erection loss may be partial or total depending on the extent of damage to the blood vessels and the nerves.

6) Hypoglycemia:  is a condition wherein the blood sugar falls below 70 mg/dcl.-- ie. much below the lower normal limit. This is more commonly seen in diabetics who developed an  unstable  diabetes where the blood sugar levels vary wildly. For a detailed post on causes, symptoms, treatment and care, of Hypoglycemia  read my “Diabetes and Hypoglycemia ”

7) Diabetic nephropathy: As explained earlier, in diabetes, the blood vessels and the nerves are also damaged. As a result , this has a heavy toll on the kidneys.

              As the blood vessels get thickened, the blood flow to the kidneys is reduced.  The  filtration process of the blood by the kidneys is impaired. Protein thus leaks into the urine, which is a sign of kidneys beginning to get damaged,

             If the nerves supplying the kidney get damaged in diabetes, the sensation of the bladder being  full, is lost. As a result , the urge to urinate is lost and the urine collects in the bladder till the bladder becomes completely full.

            The urine passes without the patient realizing it . This is called urinary incontinence. Similarly, urine also collects in the kidneys for a long time . This results in infection setting in the kidneys and the bladder.         The kidneys do not function properly and ultimately the kidneys fail.       

Cool Digestive complications of diabetes  : As a result of diabetic neuropathy, the nerves which supply the various parts of the digestive tract may also be affected. Depending on the nerve   and the part it supplies, complications pertaining to that part occur.

A] Eesophagus: difficulty in swallowing

B] Stomach ;

1) As a result of loss of nervous control on the stomach, food in the stomach empties slowly. Digestion does not take place properly.

2) There is persistent nausea and vomiting.

3) Distention of the stomach and loss of appetite.

4) As food is not properly digested, Levels of glucose fluctuate widely.

C] Intestine: Constipation alternates with uncontrolled diarrhea giving rise to loss of weight’     
                                                                                   


9)   Foot complications in diabetes: as explained earlier, in diabetes, two complications occur:
     (1) Reduced blood supply due to clogging of arteries
(2) Nerve damage due to reduced blood supply to the nerves

As a result of these two complications occurring in the lower extremities, there is reduced sensation and reduced blood supply to the foot. The pain of  an  injury is not felt, and therefore the injury tends to get neglected.

As a result of the reduced blood supply to the foot, the  white blood cells do not reach the site of injury in sufficient quantity  and therefore the defense  mechanism is not efficient enough to fight the infection.

Moreover, the high  glucose  content in the blood helps the bacteria to grow fast. Infection spreads and the injury  worsens as the medicines given, cannot reach the site of infection in the full dosage. The wound deepens and the infection may spread to the bones resulting in osteomylitis.  In serious cases, amputation may be the only surgical remedy.                                                                     

                                           

 




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« Reply #8 on: December 07, 2010, 02:46:43 am »

Diabetes mellitus type 2 – formerly non-insulin-dependent diabetes mellitus (NIDDM) or adult-onset diabetes – is a metabolic disorder that is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency.[2] Diabetes is often initially managed by increasing exercise and dietary modification. As the condition progresses, medications may be needed.
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