High frequency oscillation for ARDS

[kkmalaysia]

A systematic review and meta-analysis has supported the use of high frequency oscillation (HFO) rather than conventional mechanical ventilation (CMV) for patients with acute lung injury/ acute respiratory distress syndrome (ARDS).

The analysis included eight trials (419 adults or children with ARDS). HFO improved oxygenation by 24%, 16%, and 17% at 24, 48, and 72 hours compared with CMV. Hospital (or 30 day) mortality was reduced by 23% and treatment failure by 33%.

Compared with CMV, HFO reduced mortality and treatment failure rates and improved oxygenation. Editorialists advise caution in the adoption of HFO until more evidence is available.

Source: Medical Progress