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Author Topic: new vaccine HPV? vaccine claimed to prevent cervix cancer..  (Read 3661 times)
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albertO de ca Topic starter
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« on: April 08, 2007, 10:03:34 am »

dear friend, recently emerged an new vaccine claimed can prevent cervical cancer.
maybe we should keep update with this new updates. coz soon will be more and more ppl know regarding this and ask about this issue..
below are some information regarding this topic..
enjoy reading  Grin


Human papilloma viruses (HPV) are extremely common sexually transmitted infections. In more than 90 percent of cases, the infections are harmless and go away without treatment.

However, certain types of HPV increase women’s risk for cancer of the cervix (the neck of the womb). HPV-16, the virus type that was the focus of the current study, is found in 50 percent of cervical cancers. About a dozen other HPV types are involved in most other cases of the disease.


The study involved 2,392 women from 16 to 23 years in age. Participants were randomly assigned to receive three shots of either an HPV-16 vaccine or a placebo (a dummy substance). The study was double-blinded Participants were followed for an average of 17 months after getting the third shot.

Some women had HPV-16 infections or other cervical abnormalities when they enrolled in the study; others developed the infection before they received all three shots. These women (859 enrollees) were excluded when the researchers calculated the vaccine’s effectiveness.

Of the remaining 1,533 women, 41 developed HPV-16 infection -- all of these women were in the placebo group. Nine of the 41 women with HPV-16 infection went on to develop precancerous lesions (areas of abnormal tissue that may become cancerous). Twenty-two other women from the placebo group also developed precancerous lesions on their cervixes, but these were not associated with HPV-16.

By comparison, no one who got all three vaccine shots developed an HPV-16 infection. Twenty-two women receiving the vaccine did develop cervical abnormalities that can lead to cancer but these precancerous lesions were not associated with HPV-16.

Limitations

The vaccine tested in this study has several limitations, noted NCI’s Hildesheim. For one thing, the vaccine offers no protection against other types of HPV that can also cause cervical cancer. In addition, it’s unknown whether the vaccine’s protection against HPV-16 is long-lasting. Finally, it does not prevent HPV-16 infections already present at the time of vaccination from progressing to cancer.

The study, which was supported by Merck Research Laboratories, will continue until all the participants have been followed for four years. Laura A. Koutsky, Ph.D., of the University of Washington in Seattle, led the team of researchers who conducted this study. An editorial by Christopher P. Crum, M.D., of Brigham and Women's Hospital in Boston accompanies the report. There are other efforts to develop a cervical cancer vaccine, as well, including one trial sponsored by NCI that is not yet open to enrollment.

Pap Tests Still Needed

Most cervical cancers develop slowly through a series of abnormal changes in the cells of the cervix, changes most often related to an HPV virus. Regular Pap tests can detect these changes and the abnormal tissue can be removed. Pap tests would still be needed even if the experimental vaccine used in this study proves widely effective because the vaccine only works against one kind of HPV.

Pap tests are not 100 percent accurate, however, and many women do not have the tests regularly. In one national health survey, a fifth of women aged 18 to 64 had not had a Pap test in the past three years. A vaccine that prevented the HPV infections known to be behind most cervical cancers would be a powerful addition to disease prevention strategies.

other readings:
http://www.cdc.gov/std/hpv/STDFact-HPV-vaccine.htm

http://www.washingtonpost.com/wp-dyn/content/discussion/2007/01/16/DI2007011600929.html?nav=rss_health

 i am now trying to find other papers regarding this and if possible, i will  post soon! thanks for reading.   Wink

« Last Edit: April 08, 2007, 10:13:29 am by Admin » Logged
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« Reply #1 on: April 08, 2007, 10:12:02 am »

For those who don't know, infection of the cervix by viruses called Human Papilloma Virus (HPV) is known to caused pre-cancerous lesion which can further progress to cervical cancer. Therefore, vaccination against the infection will in turn prevent cervical cancer.
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stabilo
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« Reply #2 on: April 09, 2007, 09:15:35 am »

so is the vaccine cost effective?
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albertO de ca Topic starter
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« Reply #3 on: April 11, 2007, 11:06:44 pm »

so is the vaccine cost effective?
hey. happy to hear from you..
hmmm according to the articles, they did not mention about the cost. however, there is one friend of mine, tell me that she was told regarding this vaccine, and need about few hundred RM for 1 injection.. And the doctor actually told her that the price is after subsidise by goverment. I  not sure about that, however, i think according to the articles, the number to treat (NTT) is quite loh.. so should be ok kua..
but personally i think is far too expensive and we dont know either just covering a few trend of virus will actually prevent totally from cervix cancer loh..
so i think i will try find out more regarding this trial..

keep u updates ya..

take k

best regards,
Albert Lee
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zpt
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« Reply #4 on: April 15, 2007, 10:21:03 pm »

so is the vaccine cost effective?
hey. happy to hear from you..
hmmm according to the articles, they did not mention about the cost. however, there is one friend of mine, tell me that she was told regarding this vaccine, and need about few hundred RM for 1 injection.. And the doctor actually told her that the price is after subsidise by goverment. I  not sure about that, however, i think according to the articles, the number to treat (NTT) is quite loh.. so should be ok kua..
but personally i think is far too expensive and we dont know either just covering a few trend of virus will actually prevent totally from cervix cancer loh..
so i think i will try find out more regarding this trial..

keep u updates ya..

take k

best regards,
Albert Lee

How many injection needed to confer protection against HPV?
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albertO de ca Topic starter
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« Reply #5 on: April 16, 2007, 12:04:08 am »

according to the articles from thier research, need 3 injections..
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alfred98
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« Reply #6 on: April 16, 2007, 03:53:05 pm »

Gahment should make it compulsory for every female to be injected.....But hor...who gonna pay hor???
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mdmjane
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« Reply #7 on: April 16, 2007, 08:01:52 pm »

My freind just passed away beacuse of cervical cancer. I am abit worried now. Is it too late for me to take the vaccine?
Any expert? Please advise.
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alfred98
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« Reply #8 on: April 30, 2007, 12:54:41 pm »

My freind just passed away beacuse of cervical cancer. I am abit worried now. Is it too late for me to take the vaccine?
Any expert? Please advise.
How old are U and are U sexually active???
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mdmjane
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« Reply #9 on: May 03, 2007, 01:27:52 pm »

My freind just passed away beacuse of cervical cancer. I am abit worried now. Is it too late for me to take the vaccine?
Any expert? Please advise.
How old are U and are U sexually active???

I am 48. I have sex with my husband 1 to 3 times per week. Am I considered sexually active?  Huh?
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